Deficits on self ordered tasks associated with hyperostosis frontalis interna
a Centre for Magnetic Resonance, b Department of
Psychology, The University of Queensland 4072, Australia, c Department of Medicine, The University
of Queensland, Princess Alexandra Hospital, Woolloongabba 4102, Australia, d SmithKline Beecham
Pharmaceuticals, Clinical Pharmacology Unit, New Frontiers Science
Park, Third Avenue, Harlow, Essex CM19 5AW, UK
Correspondence to: Dr Jonathan B Chalk, Department of Medicine, The University of Queensland, Princess Alexandra Hospital, Woolloongabba 4102, Australia.
Received 2 January
1997 and in revised form 2 April 1997;
Accepted 4 April 1997
A 74 year old patient, EW, with dorsolateral frontal cortical
compression due to hyperostosis frontalis interna, in the absence of
the Morgagni or Stewart-Morel syndromes, is described. In addition to
conventional neuropsychological measures EW was administered one
non-spatial and two spatial self ordered working memory tasks, as well
as a standard measure of fluid intelligence or g. She showed impaired
performance on all three self ordered working memory tasks compared
with a normal control group of 10 subjects matched for age, education,
sex, and IQ. By contrast, her performance on the fluid intelligence
test was comparable with that of the controls. It is concluded that
the compression of dorsolateral frontal cortex accompanying
hyperostosis frontalis interna may produce selective cognitive impairment.
© 1997 by Journal of Neurology, Neurosurgery, and Psychiatry
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