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a Université de
Bourgogne, Dijon, France, b CNRS
UMR 7395, Hôpital de la Salpêtrière, Paris, France
Correspondence to: Dr Catherine Bungener, CNRS UMR 7395, Hôpital de la Salpêtrière, 47 Bd de l'Hôpital, 75013 Paris, France. Telephone 0033 1 44 23 07 50; fax 0033 1 53 70 07 70; email: bungene{at}ext.jussieu.fr
Received 13 August
1997 and in revised form 24 February 1998;
Accepted 27
February 1998
OBJECTIVE
To evaluate
psychopathological disturbances in patients with myotonic dystrophy
(MD) and compare patients with MD to both patients with
facioscapulohumeral dystrophy (FSHD) and healthy control subjects.
METHODSA
semistructured interview was used to determine DSM III-R criteria for
major depressive episodes, dysthymic episodes, and generalised anxiety.
The Montgomery and Asberg and the Hamilton depressive scales, the Covi
and Tyrer anxiety scales, the Abrams and Taylor scale for emotional
blunting, and the depressive mood scale were all used in the study.
Subjects were also asked to complete questionnaires for physical and
social anhedonia.
RESULTSFifteen
patients with MD, 11 patients with FSHD, and 14 healthy subjects were
studied. Patients with MD were not more depressed or anxious than
healthy controls. Patients with FSHD were the most depressed and most
anxious. However, patients with MD had significantly lower scores for
expressiveness and significantly higher scores for anhedonia than the
other two groups.
CONCLUSIONPatients
with MD did not present significant depressive or anxious
symptomatology but rather an emotional deficit. This emotional deficit
may be an adaptive reaction to the threatening implications of the
disease, or the effect of the CNS lesions which occur with MD, or both.
This article has been cited by other articles:
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  S.R. Montel and C. Bungener Coping and quality of life in one hundred and thirty five subjects with multiple sclerosis Multiple Sclerosis, April 1, 2007; 13(3): 393 - 401. [Abstract] [PDF]
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 C Ertekin, N Yuceyar, I Aydogdu, and H Karasoy Electrophysiological evaluation of oropharyngeal swallowing in myotonic dystrophy J. Neurol. Neurosurg. Psychiatry, March 1, 2001; 70(3): 363 - 371. [Abstract] [Full Text] [PDF]
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