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a Department of
Neurology, Ludwig-Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany, b Department of Neuroradiology, c Institute of Neuropathology, d Department
of Neurology, Bezirkskrankenhaus Gabersee, Reitmehring, Germany, e Department of Neuropathology,
University of Bonn, Germany
Correspondence to: Dr Hans Walter Pfister Pfister{at}nefo.med.uni-muenchen.de
Received 23 December
1999 and in revised form 13 April 2000;
Accepted 13 April
2000
A 28 year old man presented with a 1 month history of symptoms
of intracranial hypertension. Examination showed bilateral papilloedema
and meningeal signs. Magnetic resonance imaging showed nodular lesions
on the cerebellar and pontine surface and thickening of the thoracic
spinal leptomeninges. Throughout the course of the disease, contrast
enhancement was detected in the spinal leptomeninges but not
intracranially. Primary diffuse leptomeningeal gliomatosis (PDLG) was
diagnosed by biopsy and later confirmed on necropsy. The present case
is remarkable for the nodular superficial cerebellar lesions and the
absence of intracranial contrast enhancement of the leptomeninges.
This article has been cited by other articles:
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  A Baborie, E M Dunn, L R Bridges, and J M Bamford Primary diffuse leptomeningeal gliomatosis predominantly affecting the spinal cord: case report and review of the literature J. Neurol. Neurosurg. Psychiatry, February 1, 2001; 70(2): 256 - 258. [Abstract] [Full Text] [PDF]
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