| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS | REGISTER |
|
|
|
|
|||||||||||||
|
|
|||||||||||||||
a Department of
Neurology, Johns Hopkins University School of Medicine, 600 North Wolfe
Street, Baltimore, MD 21287, USA, b Johns Hopkins School of Public Health, c Department of Neurosurgery
Correspondence to: Dr Daniele Rigamonti drigamon{at}welchlink.welch.jhu.edu
Received 13 August
1999 and in revised form 13 March 2000;
Accepted 21 March
2000
OBJECTIVES
To
determine the frequency and severity of neuropsychological impairments
associated with aneurysmal subarachnoid haemorrhage, and associated
with repair of intracerebral aneurysms.
METHODSTwo groups of
patients who underwent repair of intracerebral aneurysms were studied:
patients with unruptured aneurysms (n=20) and patients with ruptured
aneurysms (n=27). All patients were administered a battery of
standardised neuropsychological tests about 3 months after surgery. A
subset of 12 patients with unruptured aneurysms were administered the
battery both before and after elective repair of the aneurysm(s). A
subset of six patients with ruptured aneurysms were given the test at
both 3 months and 1 year after surgery.
RESULTSAs previously
reported for patients with ruptured aneurysms, patients with both
ruptured and unruptured aneurysms performed, as a group, significantly
below published norms on many of the neuropsychological tests after
surgery. However, there were significant differences between
preoperative and postoperative performance in the unruptured aneurysm
group only on a few tests: measures of word fluency, verbal recall, and
frontal lobe function. Performance of patients with ruptured aneurysms
was significantly below that of patients with unruptured aneurysms only
on a few tests of verbal and visual memory. In addition, group
differences compared with published norms reflected severely impaired
performance by a minority of patients, rather than moderately impaired
performance in a majority of patients.
CONCLUSIONSAlthough
patients who undergo repair of ruptured aneursyms perform, as a group,
below published norms on many neuropsychological tests, significant
impairments are seen in a minority of patients. Some of the impairments
are associated with subarachnoid haemorrhage, whereas others (found in
patients who underwent repair of unruptured aneurysms) are due to
general effects of neurosurgery and perioperative management. Finally,
some of the postoperative deficits are merely a reflection of premorbid weaknesses.
This article has been cited by other articles:
|
|
 |
|
  L. A. Lanterna, M. Rigoldi, G. Tredici, F. Biroli, C. Cesana, S. M. Gaini, and L. Dalpra APOE influences vasospasm and cognition of noncomatose patients with subarachnoid hemorrhage Neurology, April 12, 2005; 64(7): 1238 - 1244. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J Powell, N Kitchen, J Heslin, and R Greenwood Psychosocial outcomes at 18 months after good neurological recovery from aneurysmal subarachnoid haemorrhage J. Neurol. Neurosurg. Psychiatry, August 1, 2004; 75(8): 1119 - 1124. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Tuffiash, R. J. Tamargo, and A. E. Hillis Craniotomy for Treatment of Unruptured Aneurysms Is Not Associated With Long-Term Cognitive Dysfunction Stroke, September 1, 2003; 34(9): 2195 - 2199. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J Powell, N Kitchen, J Heslin, and R Greenwood Psychosocial outcomes at three and nine months after good neurological recovery from aneurysmal subarachnoid haemorrhage: predictors and prognosis J. Neurol. Neurosurg. Psychiatry, June 1, 2002; 72(6): 772 - 781. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. T. Kreiter, D. Copeland, G. L. Bernardini, J. E. Bates, S. Peery, J. Claassen, Y. E. Du, Y. Stern, E. S. Connolly, S. A. Mayer, et al. Predictors of Cognitive Dysfunction After Subarachnoid Hemorrhage * Editorial Comment Stroke, January 1, 2002; 33(1): 200 - 209. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. CARPENTER Aneurysmal haemorrhage: partialling out the effect of the bleed J. Neurol. Neurosurg. Psychiatry, November 1, 2000; 69(5): 572a - 573. [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS | REGISTER |
