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Journal of Neurology, Neurosurgery, and Psychiatry 2002;72:144-149; doi:10.1136/jnnp.72.2.144
Copyright © 2002 by the BMJ Publishing Group Ltd.
Journal of Neurology Neurosurgery and Psychiatry 2002;72:144-149
© 2002 Journal of Neurology Neurosurgery and Psychiatry

EDITORIAL

New mitochondrial disorders

The "new" mitochondrial disorders

A H V Schapira

University Department of Clinical Neurosciences, Royal Free and University College Medical School, and Institute of Neurology, University College London, London NW3 2PF, UK

Correspondence to:
Correspondence to:
A H V Schapira;
Schapira{at}rfc.ucl.ac.uk

ABSTRACT

The "new" mitochondrial disorders

Keywords: mitochondria, apoptosis; Parkinson's disease, Huntington's disease, Friedreich's ataxia

Abbreviations: MITOX, mitochondrial oxidative phosphorylation system; mtDNA, mitochondrial DNA; rRNA, ribosomal RNA; tRNA, transfer RNA; ANT-1, gene for the heart/skeletal muscle isoform of the adenine nucleotide translocator; MNGIE, mitochondrial neurogastrointestinal encephalomyopathy; GAA, guanine-adenine-adenine; YFH1, yeast frataxin homologue 1; CAG, cytosine-adenine-guanine; SOD-1, superoxide dismutase 1; OH8dG; 8-hydroxy-2-deoxyguanosine; 31P-MRS; 31-phosphorus magnetic resonance spectroscopy


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