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PAPER |
1 University Maastricht, Maastricht, The Netherlands
2 University Glasgow, Glasgow, Scotland
3 Leiden University Medical Centre, Leiden, The Netherlands
4 University Cork, Cork, Ireland
Correspondence to:
Correspondence to:
Dr R G J Westendorp, Section of Gerontology and Geriatrics, Leiden University Medical Center, C-2-R, PO box 9600, 2300 RC Leiden, The Netherlands;
R.G.J.Westendorp{at}LUMC.nl
Methods: In the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER), 5804 elderly subjects aged 70 to 82 years were examined using a learning test (memory), a coding test (general speed), and a short version of the Stroop test (attention). Data presented here were collected at dual baseline, before randomisation for active treatment.
Results: The tests proved to be reliable (with test/retest reliabilities ranging from acceptable (r=0.63) to high (r=0.88) and sensitive to detect small differences in subjects from different age categories. All tests showed significant practice effects: performance increased from the first measurement to the first follow up after two weeks.
Conclusion: Normative data are provided that can be used for one time neuropsychological testing as well as for assessing individual and group change. Methods for analysing cognitive change are proposed.
Keywords: cognition testing; reliability; practice effects; elderly people
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