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Magnetic resonance imaging abnormalities with septic encephalopathy

Departments of Neurology and Pathology, Hartford Hospital, University of Connecticut School of Medicine, Hartford, CT, USA

Correspondence to:
Correspondence to:
P F Finelli MD
Hartford Hospital, 80 Seymour Street, Hartford, CT 06102-5037, USA; Pfinell{at}harthosp.org

ABSTRACT
A 48 year old woman, status post renal transplantation six years earlier, died after a two week illness characterised by fever, recurrent seizures, and coma. Widespread abnormalities were seen on neuroimaging. A diagnosis of septic encephalopathy was established on postmortem. We describe the magnetic resonance imaging findings of bilateral basal ganglia, thalamic, cerebellar, brainstem, and cerebral abnormalities in this patient, which correlate with the pathophysiology of septic encephalopathy.

Abbreviations: CT, computed tomography; FLAIR, fluid attenuated inversion recovery; MRI, magnetic resonance imaging; SE, septic encephalopathy

Keywords: septic encephalopathy; MR imaging; neuropathology