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Occipital activation in glyceryl trinitrate induced migraine with visual aura

Headache Group, Institute of Neurology and The National Hospital for Neurology and Neurosurgery Queen Square, London WC1, UK

Correspondence to:
Correspondence to:
Professor Peter J Goadsby
Headache Group, Institute of Neurology, Queen Square, London WC1N 3BG, UK, peterg{at}ion.ucl.ac.uk

ABSTRACT
A case of migraine is presented with visual aura triggered on two separate occasions by glyceryl trinitrate (GTN). Positron emission tomography was carried out during the second triggering session. Activation in the primary visual area of the occipital cortex was demonstrated during the aura. This is the first published case of migraine aura triggered reproducibly by GTN.

Abbreviations: GTN, glyceryl trinitrate; HIS, International Headache Society

Keywords: PET; migraine; glyceryl trinitrate; nitric oxide

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