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Cerebellar hypermetabolism in paraneoplastic cerebellar degeneration

¹ Department of Neurology, Seoul National University College of Medicine, Seoul, Republic of Korea
² Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
³ Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands

Correspondence to:
Correspondence to:
Dr Ji Soo Kim
Department of Neurology, College of Medicine, Seoul National University and Bundang Hospital, 300 Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-707, Republic of Korea; jisookim{at}snu.ac.kr

ABSTRACT
A 51 year old man with paraneoplastic cerebellar degeneration from gastric adenocarcinoma showed cerebellar hypermetabolism and increased perfusion on brain FDG-PET scan and SPECT during the acute stage of his illness. The patient underwent subtotal gastrectomy. The intensity of the hypermetabolism had decreased markedly on follow-up FDG-PET 3 months later following two cycles of chemotherapy. We suggest that the cerebellar hypermetabolism may have been due to an acute inflammatory process associated with an immunological reaction.

Abbreviations: CSF, cerebrospinal fluids; PCD, paraneoplastic cerebellar degeneration

Keywords: cerebellar hypermetabolism; FDG PET; paraneoplastic cerebellar degeneration

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Paraneoplastic cerebellar degeneration: new insights into imaging and immunology

J H Rees
J. Neurol. Neurosurg. Psychiatry 2006 77: 427. [Extract] [Full Text] [PDF]

This article has been cited by other articles:

				J H Rees Paraneoplastic cerebellar degeneration: new insights into imaging and immunology J. Neurol. Neurosurg. Psychiatry, April 1, 2006; 77(4): 427 - 427. [Full Text] [PDF]