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Clinical insights into paraneoplastic cerebellar degeneration

¹ Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, and Day Clinic of Cognitive Neurology, University of Leipzig, Germany
² Department of Palliative Medicine, University of Cologne, Cologne, Germany
³ Department of Gynaecology, University of Leipzig
⁴ Department of Nuclear Medicine, University of Leipzig

Correspondence to:
Correspondence to:
Dr Rainer Scheid
Day Clinic of Cognitive Neurology, University of Leipzig, Liebigstr 22a, 04103 Leipzig, Germany; scheid{at}cbs.mpg.de

ABSTRACT
Neuroimaging is usually unremarkable in paraneoplastic cerebellar degeneration (PCD), at least in the early stages of the disease. A patient with proven PCD is reported in whom it could be shown that cerebellar atrophy evolved very rapidly and was present in early imaging studies. Even with the use of the whole spectrum of modern diagnostic tools, the underlying malignancy can be difficult to diagnose. In addition to mammography, MRI is recommended in these cases and repeat FDG-PET may be necessary.

Abbreviations: FDG, fluorodeoxyglucose; PCD, paraneoplastic cerebellar degeneration

Keywords: cerebellar atrophy; FDG-PET; MRI; paraneoplastic cerebellar degeneration

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Paraneoplastic cerebellar degeneration: new insights into imaging and immunology

J H Rees
J. Neurol. Neurosurg. Psychiatry 2006 77: 427. [Extract] [Full Text] [PDF]

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				J H Rees Paraneoplastic cerebellar degeneration: new insights into imaging and immunology J. Neurol. Neurosurg. Psychiatry, April 1, 2006; 77(4): 427 - 427. [Full Text] [PDF]