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Dura mater-associated Creutzfeldt–Jakob disease: experience from surveillance in the UK

¹ National CJD Surveillance Unit, University of Edinburgh, Edinburgh, UK
² Cambridge Centre for Brain Repair, University of Cambridge, Cambridge, UK
³ Royal Victoria Hospital, Belfast, UK
⁴ Harley Street, London, UK
⁵ Ninewells Hospital, Dundee, UK
⁶ The Royal Surrey County Hospital, Surrey, UK

Correspondence to:
Correspondence to:
Dr R S G Knight
National CJD Surveillance Unit, Bryan Matthews Building, Western General Hospital, Edinburgh EH4 2XU, UK; r.knight{at}ed.ac.uk

ABSTRACT
Between 1970 and 2003, seven cases of human dura mater-associated Creutzfeldt–Jakob disease (CJD) were identified in the UK. Furthermore, we identified a case of CJD in a porcine dura graft recipient. The mean incubation period of the human dura mater cases was 93 (range 45–177) months. The clinico-pathological features of the cases are described and compared with cases previously reported in the world literature.