NEUROLOGY OF BODY SYSTEMS

Haematology and neurology

Steven Austin¹, Hannah Cohen², Nick Losseff³

¹ Department of Haematology, University College London, London, UK
² University College London Hospitals NHS Foundation Trust, London, UK
³ The Whittington and The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK

Correspondence to:
Correspondence to:
Dr Nick Losseff
The Whittington and The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, University College London, Gower Street, London WC1E 6BT, UK; nicholas.losseff{at}uclh.nhs.uk

This review aims to update the reader on advances in the understanding of haematological conditions that may arise in neurological practice. Thrombophilia, antiphospholipid antibody syndrome, thrombotic thrombocytopenic purpura, sickle cell and clonal disorders associated with neuropathy are discussed.

Abbreviations: aPL, antiphospholipid antibodies; APS, antiphospholipid syndrome; FVL, factor V Leiden; HIT, heparin induced thrombocytopenia; IL, interleukin; LA, lupus anticoagulant; MGUS, monoclonal gammopathy of undetermined significance; MTHFR, methylene tetrahydrofolate reductase; PFO, patent foramen ovale; POEMS, polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes; PTGM, prothrombin gene mutation; TTP, thrombotic thrombocytopenic purpura; VTE, venous thromboembolism; VWF, Von Willebrand factor; WM, Waldenströms macroglobulinaemia

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