Neurology in medicine
Neurology and the liver
a Department of
Gastrointestinal and Liver Diseases, Academic Medical Center, 1105 AZ
Amsterdam, The Netherlands, b Neurologische
Klinik, Medizinische Hochschule Hannover, 30623 Hannover, Germany
Correspondence to: Dr E A Jones, Academisch Medisch Centrum, Department of Gastrointestinal and Liver Diseases, Room C2-330, Meibergdreef 9, 1105 AZ Amsterdam Zuidoost, The Netherlands.
| The first 150 words of the full text of this article appear below. |
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Introduction |
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Neurological syndromes commonly occur in patients with liver
disease. A neurological syndrome associated with a liver disease may be
a complication of the disease, it may be induced by a factor that also
contributes to the disease
for example, alcoholor it may have no
relation to the presence of the liver disease. Neurological deficits
associated with liver disease may affect the CNS, the peripheral
nervous system, or both. This review focuses on syndromes characterised
by altered CNS function associated with structural liver diseases.
Space does not permit consideration of peripheral neuropathies
associated with liver disease (for example, xanthomatous peripheral
neuropathy), diseases of childhood that affect the liver and CNS (for
example, Reye's syndrome), or neurological consequences of hepatic
lesions characterised by specific enzyme deficiencies (for example,
congenital hyperammonaemias, the porphyrias, kernicterus,
galactosaemia, and Zellweger's syndrome (cerebrohepatorenal syndrome)).
That there is a relationship between the functional status of the liver
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