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Journal of Neurology, Neurosurgery, and Psychiatry 1997;63:548-549; doi:10.1136/jnnp.63.4.548
Copyright © 1997 by the BMJ Publishing Group Ltd.
J Neurol Neurosurg Psychiatry 1997;63:548-549 ( October )

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Transient semantic amnesia: a new syndrome?

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The term transient global amnesia was first coined by Fisher and Adams in 1964 to describe a clinical syndrome characterised by the abrupt onset of severe amnesia usually accompanied by repetitive questioning, occurring in middle aged or elderly people, and lasting several hours.1 The aetiology of transient global amnesia has been a topic of debate, but in the past few years the situation has become considerably clearer with the emergence of the following diagnostic criteria: (1) attacks must be witnessed and information available from an observer who was present for most of the attack, (2) there must be clear cut anterograde amnesia during the attack, (3) clouding of consciousness and loss of personal identity must be absent and the cognitive impairment limited to amnesia, (4) there should be no accompanying focal neurological symptoms and functionally relevant focal signs, (5) epileptic features must be absent, (6) attacks must resolve within 24 hours, and . . . [Full text of this article]


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