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a Department of
Clinical Neurosciences, b Neuropathology Laboratory, Department of
Clinical Neurosciences, Western General Hospital, Crewe Road,
Edinburgh, UK, c Department of
Neurology, University of Utrecht, Box 85500, 350GA Utrecht, The
Netherlands
Correspondence to: Dr Nicolas U Weir, Department of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, Scotland, UK. Telephone 0044 131 343 6630; fax 0044 131 332 5150; email nuw@skull.dcn.ed.ac.uk
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Case presentation |
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A 65 year old, right handed, retired police inspector presented to
hospital as an emergency. That afternoon, while decorating, he had
complained of a headache, although it did not prevent him from
continuing with his work. Three hours later, however, his wife found
him unable to speak, with a drooped right face and shortly afterwards,
complete right sided paralysis. He was known to have hypertension and,
3 months earlier, he had been investigated for weight loss and painless
obstructive jaundice. Endoscopic retrograde cholangiopancreatography
(ERCP) had shown an impacted gall stone and appearances consistent with
a periampullary tumour, although no histology was obtained.
Sphincterotomy had led to improvement and the diagnosis had not been
pursued further. Routine screening had also disclosed a lymphocytosis
of 8.25×109 /l, which was confirmed to be due to an
asymptomatic, early chronic lymphocytic leukaemia. His medications
consisted of 100 mg atenolol daily, 25 mg mefruside daily, and 400 mg
cimetidine twice
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