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a Respiratory Muscle
Laboratory, Correspondence to: Dr Mike Polkey, Respiratory Muscle Laboratory, King's College
Hospital, Bessemer Road, London SE5 9PJ, UK. Telephone 0044 171 346 4493; fax 0044 171 346 3589; email michael.polkey@kcl.ac.uk
Received 5 February 1998 and in revised form 7 August
1998;
Accepted 25 August 1998 Exertional
dyspnoea is commonly an early feature in respiratory disease; however,
neurological disease may limit mobility and, as a consequence, preclude
this symptom. Diagnosis of respiratory dysfunction resulting from
neurological disease may therefore require a higher index of clinical
suspicion or the application of specific tests; this exercise is
worthwhile if it allows advance detection and discussion and (where
appropriate) treatment, of impending overt respiratory dysfunction.
Specific symptoms and appropriate tests will be discussed in the text
and have also been reviewed in detail elsewhere.1 However,
it should be recalled that, at the most basic level, the function of
the respiratory muscle pump is to produce inspiratory airflow, which is
related to the ability to generate a subatmospheric pressure within the thorax. Thus, although access to detailed investigation of respiratory muscle is not universal, we encourage measurement of both the lying and
standing vital capacity2 and static mouth/nasal
pressures,3 4 which
The first 150 words of the full text of this article appear below.
Introduction
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