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Journal of Neurology, Neurosurgery, and Psychiatry 1999;67:281; doi:10.1136/jnnp.67.3.281
Copyright © 1999 by the BMJ Publishing Group Ltd.
J Neurol Neurosurg Psychiatry 1999;67:281 ( September )

Editorial commentary

Deep brain stimulation in Parkinson's disease

The first 150 words of the full text of this article appear below.

This issue of the Journal sees the publication of two papers that increase our knowledge of the functions of the internal architecture of the thalamus and globus pallidus---an important achievement given the existing literature on stereotactic functional surgery for Parkinson's disease.

The paper by Caparros-Lefebvre et al1 (pp 308-14) is fascinating, because one would have expected that after nearly 50 years of thalamic surgery every possible internal thalamic target would have been explored. However, the surgical outcomes have not always been studied carefully, or published for others to share. Caparros-Lefebvre et al compared the functional results and electrode positions obtained by two teams performing thalamic stimulation for parkinsonism. Anatomical comparisons were possible because ventriculography had been performed by both groups. The two teams used similar techniques for the implantation of electrodes into the ventralis intermedius nucleus of the thalamus (VIM), although there were minor differences in the approach . . . [Full text of this article]


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Relevant Articles

Improvement of levodopa induced dyskinesias by thalamic deep brain stimulation is related to slight variation in electrode placement: possible involvement of the centre median and parafascicularis complex
Dominique Caparros-Lefebvre, Serge Blond, Marie-Pierre Feltin, Pierre Pollak, Alim Louis Benabid
J. Neurol. Neurosurg. Psychiatry 1999 67: 308-314. [Abstract] [Full Text] [PDF]

Acute and chronic effects of anteromedial globus pallidus stimulation in Parkinson's disease
Franck Durif, Jean-Jacques Lemaire, Bérengère Debilly, Gérard Dordain
J. Neurol. Neurosurg. Psychiatry 1999 67: 315-322. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

  • Vesper, J, Chabardes, S, Fraix, V, Sunde, N, Ostergaard, K (2002). Dual channel deep brain stimulation system (Kinetra) for Parkinson's disease and essential tremor: a prospective multicentre open label clinical study. J. Neurol. Neurosurg. Psychiatry 73: 275-280 [Abstract] [Full Text]  

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