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ACUTE HEAD INJURY FOR THE NEUROLOGIST

Correspondence to:
Correspondence to:
Mr PJ Hutchinson, Academic Department of Neurosurgery, University of Cambridge, Box 167, Addenbrooke’s Hospital, Cambridge CB2 2QQ, UK:
p.hutch@which.net

Keywords: acute head injury; intracranial pressure; cerebral perfusion pressure

The first 150 words of the full text of this article appear below.

Trauma is the leading cause of death in the first four decades of life, with head injury being implicated in at least half the number of cases. In the UK, 1500 per 100 000 of the population (total one million) attend accident and emergency departments with a head injury, 300 per 100 000 per year are admitted to hospital, 15 per 100 000 per year are admitted to neurosurgical units, and 9 per 100 000 per year die from head injury. Recent advances in the management of head injury have occurred at several levels including prevention, pre-hospital care, immediate hospital care, acute hospital care, and rehabilitation. This synopsis aims to outline the principles of the treatment of head injury in the acute phase.

PATHOPHYSIOLOGY
Fundamental processes occur at a cellular level following brain injury, which culminate in cell death.¹ These processes include the release of excitotoxic quantities of the amino acids, . . . [Full text of this article]

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