HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Add article to my folders Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Epstein, C M Search for Related Content PubMed PubMed Citation Articles by Epstein, C M Topic Collections Relevant Article

Dipoles and dementia

Emory Clinic, Department of Neurology, 1365 Clifton Road, Atlanta, GA 30322, USA

Correspondence to:
Correspondence to:
Dr C M Epstein;
chipstein@aol.com

Keywords: dementia; dipoles; magnetoencephalography; Alzheimer’s

The first 150 words of the full text of this article appear below.

For almost two decades magnetoencephalography (MEG) has been the stepchild of functional neuroimaging. Despite its evolution from single sensors to arrays of more than 100, with unmatched temporal resolution, the legitimacy of MEG as a clinical and research tool has been repeatedly challenged. On the one hand, neurophysiologists persistently—and appropriately—question the advantage of MEG over scalp-recorded electroencephalograms and evoked potentials when the latter are analysed by sophisticated algorithms. On the other hand, advocates of functional magnetic resonance imaging (MRI) and positron emission tomography have disparaged MEG because of the assumptions required to obtain unique solutions from magnetic field data. The paper by Maestú et al (this issue, page 208-212)¹ provides an example of work that is establishing the capabilities of MEG.

Maestú et al used MEG to compare patients with Alzheimer’s disease and elderly subjects. They had previously found that reduced MEG activation was present in left temporal . . . [Full text of this article]

Relevant Article

Do cognitive patterns of brain magnetic activity correlate with hippocampal atrophy in Alzheimer’s disease?

F Maestú, J Arrazola, A Fernández, P G Simos, C Amo, P Gil-Gregorio, S Fernandez, A Papanicolaou, and T Ortiz
J. Neurol. Neurosurg. Psychiatry 2003 74: 208-212. [Abstract] [Full Text] [PDF]