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Journal of Neurology Neurosurgery and Psychiatry 2003;74:iv32
© 2003 BMJ Publishing Group Ltd

THE MANAGEMENT OF MOTOR NEURONE DISEASE

P N Leigh1, S Abrahams1, A Al-Chalabi1, M-A Ampong1, L H Goldstein1, J Johnson1, R Lyall2, J Moxham2, N Mustfa2, A Rio1, C Shaw1, E Willey1 and the King’s MND Care Research Team

1 The King’s MND Care and Research Centre, Institute of Psychiatry, Guy’s King’s and St Thomas’s School of Medicine, and King’s College Hospital, London, UK
2 Department of Respiratory Medicine, King’s College Hospital, and Guy’s King’s and St Thomas’s School of Medicine, London UK

Correspondence to:
Correspondence to:
Professor P N Leigh
King’s MND Care and Research Centre, Department of Neurology, Institute of Psychiatry and Guy’s King’s and St Thomas’s School of Medicine, PO Box 41, Institute of Psychiatry, Denmark Hill, London SE5 8AF, UK;
n.leigh@iop.kcl.ac.uk

The first 150 words of the full text of this article appear below.

The management of motor neurone disease (MND) has evolved rapidly over the last two decades. Although still incurable, MND is not untreatable. From an attitude of nihilism, treatments and interventions that prolong survival have been developed. These treatments do not, however, arrest progression or reverse weakness. They raise difficult practical and ethical questions about quality of life, choice, and end of life decisions.

Coordinated multidisciplinary care is the cornerstone of management and evidence supporting this approach, and for symptomatic treatment, is growing.1–3 Hospital based, community rehabilitation teams and palliative care teams can work effectively together, shifting emphasis and changing roles as the needs of the individuals affected by MND evolve. In the UK, MND care centres and regional networks of multidisciplinary teams are being established. Similar networks of MND centres exist in many other European countries and in North America.

Here, we review current practice in relation to diagnosis, genetic . . . [Full text of this article]


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