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Journal of Neurology Neurosurgery and Psychiatry 2004;75:1654
© 2004 BMJ Publishing Group Ltd


BOOK REVIEW

The molecular and genetic basis of neurologic and psychiatric disease—3rd edition

M R Johnson


Edited by Roger N Rosenberg, Stanley B Prusiner, Salvatore DiMauro, Robert L Barchi, Eric J Nestler. Published by Butterworth Heinemann, London, 2003, £99.00 (hardcover), pp 823. ISBN 0-7506-7360-5

The first 150 words of the full text of this article appear below.

This is a single volume 844 page book, divided into four sections and made up of 77 chapters by 125 authors. Part I is a review of the general principles of genetic mechanisms of disease. Parts II and III cover neurological and psychiatric genetics respectively, and consist of both disease and system based chapters. Part IV is a single chapter that provides a gene map of neurological disorders. The general production values of the book are high.

The emphasis of this text is on the molecular pathogenesis of neurological and psychiatric disease, reflecting the editors’ assertion that identification of molecular pathogenesis of genetic neurological disease is "indispensable to the development of pharmacologic or gene therapy for these disorders." As such, the text will probably be of most interest to the neurologist engaged in neurogenetic research or neurogenetic counselling, than the general neurologist requiring a text that will assist him or . . . [Full text of this article]







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