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Mesencephalic ischemia and Parkinson’s disease

Neurosurgeon, Universidad Nacional Autónoma de México, Mexico City, México

Correspondence to:
Correspondence to:
Dr H Rafael
Bélgica 411 Bis, Colonia Portales, 03300, México City, México; hrtumi@yahoo.com

Keywords: mesencephalic ischaemia; Parkinsons disease

The first 150 words of the full text of this article appear below.

I read with interest the paper by Abe et al¹ on occipital and posterior parietal hypoperfusion in 28 Parkinson’s disease (PD) patients without dementia. These findings suggest that there was a reduced regional cerebral blood flow (rCBF) in the intraparenchymal territory of the posterior cerebral arteries (PCAs) probably due to the presence of atheromatous plaques located in the distal end of the basilar artery.² Atherosclerotic changes are of considerable importance because they can cause stenosis and/or occlusion at the origin of the terminal (PCAs) or collateral (superior cerebellar arteries) branches, as well as of the posterior perforating arteries (PPAs).

Based on the fact that in situ the donor tissues of catecholamines are normally highly vascularised and by contrast in PD the rCBF is reduced in the neostriatum, from February 1988 to December 2002 we have used two surgical procedures to treat PD:^3–5 (1) transplantation of adrenal medulla into the putamen . . . [Full text of this article]