© 2004 BMJ Publishing Group Ltd
CORRESPONDENCE
Tangier disease
127 Willifield Way, London NW11 6XY, UK rskocen@aol.com
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With reference to the article entitled "Tangier disease—a diagnostic challenge in countries endemic for leprosy",1 I should like to point out that the name "Tangier disease" originates from a small island in Chesapeake Bay, USA and not from Morocco as stated by the authors.
The first case of this uncommon disease with neurological involvement was reported by Kocen et al in the Lancet in 19672 and by Engel3 from the USA soon after. Detailed neuropathology on this condition in our and one other case was reported by Kocen et al in 1973.4
Competing interests: none declared
- Sinha S, Mahadevan A, Lokesh L. Tangier disease - a diagnostic challenge in countries endemic for leprosy. J Neurol Neurosurg Psychiatry 2004;75:301–4.
[Abstract/Free Full Text] - Kocen RS, Lloyd JK, Lascelles PT, et al. Familial –lipoprotein deficiency (Tangier disease) with neurological abnormalities. Lancet 1967:1341–5.
- Engel WK, Dorman JD, Levy RI, Fredrickson DS. Neuropathy in Tangier disease. Alpha-lipoprotein deficiency manifesting as familial recurrent neuropathy and intestinal lipid storage. Arch Neurol Jul 1967;17:1–9.
- Kocen RS, King RHM, Thomas PK, et al. Nerve biopsy findings in two cases of Tangier disease. Acta Neuropathol (Berl) 1973;26:317–27.[CrossRef][Medline]
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