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PITUITARY DISEASE: PRESENTATION, DIAGNOSIS, AND MANAGEMENT

Correspondence to:
Correspondence to:
Dr Andy Levy
Henry Wellcome Labs for Integrative Neuroscience & Endocrinology, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK; a.levy@bris.ac.uk

Keywords: pituitary disease; pituitary adenomas; acromegaly

The first 150 words of the full text of this article appear below.

The diagnosis of pituitary disease is generally uncomplicated. This is despite the high prevalence of occult pituitary adenomas in the general population, the widespread use of high definition imaging techniques, and the broad range of intra- and perisellar lesions that can mimic pituitary adenomas. Follow up and optimisation of pituitary hormone replacement is also relatively straightforward, but management of visual impairment, reduced fertility, coarsened facial features, arthritis, obesity, headaches, and obstructive sleep apnoea is often much more troublesome. The Pituitary Foundation (internet search term: "Pit Pat") provides important opinion and information, and reassures patients that they are not alone.

In this brief overview, the presentation, classification, and general investigation of pituitary lesions is followed by a discussion of the diagnosis and management of specific secretory subtypes.

	PRESENTATION OF PITUITARY ADENOMAS

 
Inappropriate pituitary hormone secretion and visual field deficits are the most characteristic presenting features of pituitary adenomas. Less specific symptoms such as headache, and . . . [Full text of this article]