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Journal of Neurology Neurosurgery and Psychiatry 2005;76:143-144
© 2005 BMJ Publishing Group Ltd


LETTER

Congenital dumbbell neuroblastoma mimicking birth trauma

F Nejat1, S Zabihyan Sigarchi2, M IzadYar3

1 Department of Neurosurgery, Children’s Hospital Medical Center, Tehran University of Medical Science, Tehran, Iran
2 Department of Neurosurgery, Mashad University of Medical Science, Mashad, Iran
3 Children’s Hospital Medical Center, Tehran University of Medical Science, Tehran, Iran

Correspondence to:
Correspondence to:
Dr F Nejat
No 20, West 194 (Alaii Saqarloo) Street, 3rd square of Tehran pars, Tehran, Iran; nejat@sina.tums.ac.ir

Keywords: congenital neuroblastoma; neonate; unilateral leg palsy

The first 150 words of the full text of this article appear below.

Neuroblastoma is the commonest extracranial malignant tumour in children and neonates.1 It may involve the vertebral bodies or extend into the spinal canal, compressing the spinal cord, or spread into the retroperitoneal space, involving the lumbosacral plexus. Early diagnosis is important for treatment. We report two cases of congenital neuroblastoma mimicking obstetric related palsies.


Case 1
A 4 month old baby boy with a diagnosis of unilateral leg palsy due to birth trauma, despite normal vaginal delivery, was admitted because of a palpable abdominal mass. The infant’s left leg lacked spontaneous movement, was flaccid, and deep tendon reflexes were absent. He had poor rectal tone and dribbling of urine. The levels of urinary catecholamine derivatives were increased. Spinal magnetic resonance imaging (MRI) demonstrated a large retroperitoneal mass with thoracolumbar cord involvement. A diagnosis of neuroblastoma was made following biopsy of the abdominal mass. Multiagent chemotherapy proved effective in reducing the size of . . . [Full text of this article]







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