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Imaging in epilepsy

The MRI Unit, The National Society for Epilepsy and the Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK

Correspondence to:
Correspondence to:
Professor John S Duncan
Department of Clinical and Experimental Epilepsy, Institute of Neurology, Queen Square, University College London, London WC1N 3BG, UK; j.duncan@ion.ucl.ac.uk

Keywords: magnetic resonance imaging; positron emission tomography; temporal lobe epilepsy; seizure focus; single photon emission tomography

The first 150 words of the full text of this article appear below.

The epilepsies are common serious diseases of the brain, with an age adjusted prevalence of 4–8/1000 and an annual incidence of 20–50/100 000 in developed countries. Modern neuroimaging is central to the assessment of patients with epilepsy and has dramatically modified their management. Magnetic resonance imaging (MRI) can identify substrates underlying epilepsy, and guide clinicians in the determination of treatment and prognosis. The use of x ray computed tomography (CT) has been diminished by the superior sensitivity and specificity of MRI. The results of all imaging studies should be correlated with clinical and neurophysiological data.

Epilepsies and epileptic syndromes are classified into focal and generalised. Seizures of focal origin begin in a specific cerebral area or network, most commonly in the temporal lobes. Focal epilepsies comprise 40–60% of all newly diagnosed cases. Up to 30% of these patients develop intractable epilepsy despite antiepileptic drug treatment. In patients with chronic intractable . . . [Full text of this article]

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