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Journal of Neurology, Neurosurgery, and Psychiatry 2006;77:780; doi:10.1136/jnnp.2005.084863
Copyright © 2006 by the BMJ Publishing Group Ltd.

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NEUROLOGICAL PICTURE

Acute longitudinal myelitis as the initial manifestation of Sjögren’s syndrome

T Yamamoto, S Ito, T Hattori

Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan

Correspondence to:
Correspondence to:
Dr S Ito
Department of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan; sito@faculty.chiba-u.jp

Abbreviations: MRI, magnetic resonance imaging

Keywords: Longitudinal myelitis; Sjögren’s syndrome

The first 150 words of the full text of this article appear below.

A 31 year old woman presented with sudden onset of complete paraplegia, decreased sensation for all areas below T7 spinal levels, and urinary retention. Spinal magnetic resonance imaging (MRI) showed multiple and confluent hyperintensities within the entire spinal cord extending into lower part of the medulla oblongata in T2 weighted images (fig 1Go). T1 weighted, gadolinium enhanced, images also showed multiple confluent contrast enhanced lesions within the entire spinal cord, consistent with longitudinal myelitis (fig 2Go). Laboratory data and a lip biopsy confirmed the diagnosis of Sjögren’s syndrome. As no sicca symptoms were seen in this case, acute longitudinal myelitis was considered to be the initial manifestation of Sjögren’s syndrome. Acute disseminated encephalomyelopathy and Devic’s disease were deemed unlikely because of the absence of brain and optic nerve lesions. Laboratory data excluded sarcoidosis, a disease of collagen, several infections, and metastatic tumours. Although a few cases have been . . . [Full text of this article]




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eLetters:

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JNNP Online, 23 May 2006 [Full text]



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