HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) All Versions of this Article: jnnp.2005.085365v1 77/7/805    most recent Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Add article to my folders Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Wills, A J Articles by Holmes, G K T Search for Related Content PubMed PubMed Citation Articles by Wills, A J Articles by Holmes, G K T

The neurology of enteric disease

¹ Department of Neurology, Queens Medical Centre, Nottingham, UK
² Department of Medicine, Derbyshire Royal Infirmary, Derby, UK

Correspondence to:
Correspondence to:
A J Wills
Department of Neurology, Queens Medical Centre, Nottingham NG3 5DY, UK; adewills61@hotmail.com

The first 150 words of the full text of this article appear below.

The gastrointestinal and nervous systems are intimately connected. In this article, we focus on the neurological complications of gastrointestinal, hepatic and pancreatic disease in adult patients.

THE PANCREAS
Pancreatic function is essential for the maintenance of digestive functioning and hormonal balance. The neurological consequences of diabetes are well known and will be discussed in another review in this series. Hypoglycaemia due to insulinoma may present with a changed conscious level, epilepsy, stroke-like episodes, dementia or psychosis, or neuropathy. Shaw and colleagues¹ described a 27-year-old woman with dystonic choreoathetosis. Symptoms and signs may be focal, mimicking structural lesions.

Acute pancreatitis can lead to an encephalopathy, characterised by focal signs, cognitive impairment, seizures and hallucinations.² Cerebral imaging is usually normal. Sudden blindness has also been reported secondary to a retinopathy (Purtscher’s syndrome)³ or optic neuritis.⁴ Acute pancreatitis may also lead to renal failure and an associated thrombotic microangiopathy characterised by confusion and seizures, and . . . [Full text of this article]