Journal of Neurology, Neurosurgery, and Psychiatry 2007;78:662
EDITORIAL COMMENTARY
Acute ischaemic stroke
Thrombolysis therapy in octogenarians
Stroke Unit and Division of Internal and Cardiovascular Medicine, University of Perugia, Italy
Correspondence to:
Correspondence to:
Dr Valeria Caso
Stroke Unit and Division of Internal and Cardiovascular Medicine, Ospedale Santa Maria della Misericordia, 06156 Perugia, Italy; vcaso@hotmail.com
Octogenarians can be selected for thrombolysis therapy after CT scan without a detrimental effect on outcome
| The first 150 words of the full text of this article appear below. |
In the current issue of JNNP, Ringleb et al1 report data on patients, either younger or older than 80 years, treated with systemic thrombolysis for an acute ischaemic stroke (see page 690). Interestingly, the group of octogenarians were analysed with respect to the initial imaging modality (MRI or CT). The overall rate of haemorrhage and improved efficacy outcomes was not significantly different in the two age groups and no significant difference was observed for efficacy outcomes in MRI versus CT patients.
Ringleb et al1 deal with two important issues: thrombolysis therapy in octogenarians and the search for an improved selection of patients for thrombolysis.
Acute treatment of acute stroke in octogenarians is a real challenge for stroke physicians. For many years, our primary concern has been the improvement of primary and secondary prevention and the setup of a network able to speed up hospital
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- Thrombolytic therapy for acute ischaemic stroke in octogenarians: selection by magnetic resonance imaging improves safety but does not improve outcome
- P A Ringleb, Ch Schwark, M Köhrmann, S Külkens, E Jüttler, W Hacke, and P D Schellinger
J. Neurol. Neurosurg. Psychiatry 2007 78: 690-693.[Abstract] [Full Text] [PDF]
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