HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Add article to my folders Download to citation manager Request Permissions Google Scholar Articles by Jackson, M. J PubMed PubMed Citation Articles by Jackson, M. J Related Collections Related Article

Should we accept the status quo? Time for new trials in status epilepticus

Correspondence to:
Dr M J Jackson, Department of Neurology, Royal Victoria Infirmary, Queen Victoria Rd, Newcastle upon Tyne NE1 4LP, UK; margaret.jackson@ncl.ac.uk

The first 150 words of the full text of this article appear below.

Status epilepticus (SE), defined as a seizure or series of seizures without recovery between lasting more than 30 min, takes a variety of forms, as illustrated in the report by Knake and colleagues¹ in this issue of J Neurol Neurosurg Psychiatry (see page 588). In their paper, the response to intravenous levetiracetam of 16 patients with a total of 18 episodes of status epilepticus is described. The patients were all adults; the majority of episodes of SE were complex partial and symptomatic in aetiology, a case mix that might well be seen in an acute medical admissions unit. The duration of SE is not given, a pity particularly for the patients with convulsive SE where outcome is related to duration of seizure activity. All patients received intravenous benzodiazepine, usually lorazepam, before levetiracetam. Intravenous levetiracetam was given as a bolus dose of 250–1500 mg and was associated with seizure . . . [Full text of this article]

Related Article

Intravenous levetiracetam in the treatment of benzodiazepine refractory status epilepticus

S Knake, J Gruener, K Hattemer, K M Klein, S Bauer, W H Oertel, H M Hamer, and F Rosenow
J. Neurol. Neurosurg. Psychiatry 2008 79: 588-589. [Abstract] [Full Text] [PDF]