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Journal of Neurology, Neurosurgery, and Psychiatry 2008;79:741-742; doi:10.1136/jnnp.2007.142216
Copyright © 2008 by the BMJ Publishing Group Ltd.

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A twitch of consciousness: defining the boundaries of vegetative and minimally conscious states

Quentin Noirhomme, Caroline Schnakers, Steven Laureys

Coma Science Group, Cyclotron Research Centre and Neurology Department, University of Liège, Liège, Belgium

Correspondence to:
Professor Steven Laureys, Coma Science Group, Cyclotron Research Centre and Neurology Department, University of Liège, Sart Tilman B30, 4000 Liège, Belgium; steven.laureys@ulg.ac.be

The first 150 words of the full text of this article appear below.

Some patients awaken from their coma but only show reflex motor activity. This condition of wakeful (eyes open) unawareness is called the vegetative state. In 2002, a new clinical entity coined "minimally conscious state" defined patients who show more than reflex responsiveness but remain unable to communicate their thoughts and feelings. Emergence from the minimally conscious state is defined by functional recovery of verbal or non-verbal communication.1 Our empirical medical definitions aim to propose clearcut borders separating disorders of consciousness such as coma, vegetative state and minimally conscious state but clinical reality shows that these boundaries can often be fuzzy (fig 1). Recent clinical, electrophysiological and neuroimaging studies are shedding light on these challenging limits of consciousness encountered following severe acute brain damage.


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Figure 1 Drawing sharp borders behaviourally, defining the progressive transitions from coma, to vegetative state, to minimally conscious state, to emergence from the minimally conscious state, remains . . . [Full text of this article]

 

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