Letters to the editor
Creutzfeldt-Jakob disease presenting as complex partial status epilepticus: a report of two cases
| The first 150 words of the full text of this article appear below. |
Creutzfeldt-Jakob disease is a transmissible human spongiform encephalopathy which may be familial, iatrogenic, or sporadic. The classic clinical features include a rapidly progressive dementia with the patient retaining clear consciousness until the terminal stages of the disease. We report on two patients presenting with a rapidly declining level of consciousness, in whom the clinical picture and EEG were suggestive of complex partial status epilepticus.
The first patient was a 58 year old woman who was admitted to a psychiatric unit with a short history of mood disturbance, confusion, and unsteadiness. A provisional diagnosis of agitated depression was made and she was started on lofepramine. She then became unsteady on her feet and required support when walking. She had had occasional complex partial seizures for 30 years but at presentation was not taking any anticonvulsant drugs.
On examination, she appeared perplexed, tearful, and agitated, and was
unable to give a coherent history. She
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This article has been cited by other articles:
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Fernandez-Torre, J. L.
(2005). Letter to the Editor: Creutzfeldt-Jakob Disease Presenting as Refractory Nonconvulsive Status Epilepticus. J Intensive Care Med
20: 180-181
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Shapiro, J. M.
(2005). In Response to the Letter to the Editors. J Intensive Care Med
20: 182-182
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