Letters to the editor
Myelopathy associated with Hashimoto's disease
| The first 150 words of the full text of this article appear below. |
Encephalopathy associated with Hashimoto's disease was first reported by Brain et al in 1966.1 Hashimoto's encephalopathy is a steroid responsive relapsing disorder associated with Hashimoto's disease that often presents with stroke-like episodes, myoclonus, and cognitive impairment. Diagnostic testing usually shows a euthyroid state with increased thyroid autoantibodies, increased CSF protein, and EEG abnormalities.2 3 We present the first case of myelopathy associated with Hashimoto's disease, followed 2 months later by encephalopathy.
A 70 year old housewife was admitted to our hospital on 28 July
1997. Her leg had felt heavy for a month, and she was unable to walk
for several days before admission due to weakness in the left leg. She
had been diagnosed with Hashimoto's disease at the age of 57 and
treated with thyroxin. On January 11 1988, she had developed
dysesthesia and weakness in the left arm and leg. Brain CT, radiography
of the cervical spine, and CSF findings were normal at this time.
This article has been cited by other articles:
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Ferracci, F., Moretto, G., Candeago, R. M., Cimini, N., Conte, F., Gentile, M., Papa, N., Carnevale, A.
(2003). Antithyroid antibodies in the CSF: Their role in the pathogenesis of Hashimoto's encephalopathy. Neurology
60: 712-714
[Abstract] [Full Text]
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