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Journal of Neurology, Neurosurgery, and Psychiatry 2005;76:1467-1468; doi:10.1136/jnnp.2005.062497
Copyright © 2005 by the BMJ Publishing Group Ltd.

LETTER

Excessive daytime sleepiness in migraine patients

M F P Peres1,2, M A Stiles2, H C Siow2 and S D Silberstein2

1 Hospital Israelita Albert Einstein, São Paulo, Brazil
2 Jefferson Headache Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

Correspondence to:
Correspondence to:
Dr Mario Fernando Prieto Peres
Instituto Israelita de Ensino e Pesquisa–Albert Einstein, Av Albert Einstein 627/701, São Paulo SP, Brazil; marioperes@yahoo.com

Keywords: migraine; daytime sleepiness

The first 150 words of the full text of this article appear below.

Headache and sleep disorders are related in several ways. Sleep disorders occur in headache patients, headache is a common manifestation of sleep disorders, and secondary disorders may cause headache and sleep complaints. Excessive daytime sleepiness (EDS) or excessive somnolence is a common symptom, with a prevalence of 10–20% in the general population.1

EDS is a subjective feeling of a compelling need for sleep at unusual times and in abnormal environmental conditions. Sleep deprivation, sleep fragmentation, and hypoxia are believed to be the main mechanisms leading to EDS. EDS increases the risk of car accidents, causes health status and quality of life to deteriorate, and may increase mortality. EDS is associated with obstructive sleep apnoea syndrome, brain tumours, epilepsy, stroke, degenerative diseases, trauma, multiple sclerosis, and neuromuscular disorders.1 The prevalence, mechanisms, impact, diagnosis, and treatment of EDS have never been assessed in migraine patients.

We studied 200 consecutive patients with chronic . . . [Full text of this article]


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  • Bigal, M. E., Lipton, R. B., Holland, P. R., Goadsby, P. J. (2007). Obesity, migraine, and chronic migraine: Possible mechanisms of interaction. Neurology 68: 1851-1861 [Abstract] [Full Text]  

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Sleep remits and precipitates migraine: role of the monoaminergic-vasopressin system
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