Article Text

PDF

Fatty acid composition of phospholipids from platelets and erythrocytes in multiple sclerosis
  1. S. Gul,
  2. A. D. Smith,
  3. R. H. S. Thompson,
  4. H. Payling Wright,
  5. K. J. Zilkha
  1. Department of Pharmacology, Courtauld Institute of Biochemistry, Middlesex Hospital Medical School, Royal College of Surgeons, London
  2. The National Hospital, Queen Square, London

    Abstract

    The fatty acid composition of the phospholipids of red blood cells and blood platelets has been investigated in multiple sclerosis patients and in normal individuals. The variation in the platelet phospholipid fatty acid pattern in normals has been measured for the first time and has been shown to be small. The relative level of linoleate, expressed as a percentage of the five main fatty acids, was found to be significantly lower in the multiple sclerosis patients than in healthy individuals, both in the red cells and platelets. A highly significant correlation was found between serum linoleate and both platelet and red cell linoleate.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.