In normal subjects the maximum and minimum conduction velocity along sensory nerve was the same from digit to palm and from palm to wrist. Severe slowing from palm to wrist in patients with the carpal tunnel syndrome was often associated with only slight slowing from digit to palm. The distal slowing is attributed to a reversible constriction of nerve fibres, an assumption supported by the recovery in distal conduction velocity as early as two and a half months after decompression. The sensory velocity from wrist to elbow was normal or supernormal, whereas the motor velocity was often slightly decreased. The exclusion of the normal segment of the median nerve distal to the flexor retinaculum made it possible to demonstrate abnormalities across the flexor retinaculum in patients with clinical signs of carpal tunnel syndrome in whom distal motor latency and sensory conduction from digit to wrist were normal.
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