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Clinical and pathological findings in an unusual infantile motor neurone disease
  1. Renata Kohn
  1. Department of Pathology, Government Hospital, Assaf Harofe, Zrifin, Israel

    Abstract

    An unusual motor neurone disease with a characteristic denervation atrophy of muscle is described in an infant. The striking change is a vacuolization of the cytoplasm of the affected ganglion cells in many motor nuclei of spinal cord and brain-stem, and in the claustrum. To our knowledge this disease has not yet been described in man and similar pathological changes have been found only in a certain strain of mice (`wobbler').

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