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Mechanical properties of dystrophic mouse muscle
  1. J. B. Harris1,
  2. P. Wilson2
  1. Muscular Dystrophy Group Research Laboratories, Newcastle upon Tyne General Hospital, Newcastle upon Tyne

    Abstract

    A physiological method of estimating the number of motor units in normal and dystrophic muscles has revealed a large reduction in the number of motor units in dystrophic muscles. Anatomical confirmation of the results has been obtained. Dystrophic muscles also exhibit a `myasthenic-like' response to high frequency stimulation. It is suggested that the nerve fibre is primarily affected in murine dystrophy.

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    Footnotes

    • 1 Present address: Department of Pharmacology Sölvegatan 10, S-223 62 LUND/Sweden.

    • 2 Present address: Department of Physiology and Biophysics, University of Washington School of Medicine, St. Louis, Missouri, U.S.A.

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