Article Text

PDF

Intracranial reticulum cell sarcoma associated with immunoglobulin A deficiency
  1. M. C. Gregory1,
  2. J. T. Hughes
  1. Department of Neurology, United Oxford Hospitals, Oxford
  2. Department of Neuropathology, United Oxford Hospitals, Oxford

    Abstract

    A case is reported of a 46 year old woman who died after a five month illness characterized by focal neurological signs, evidence of meningeal irritation, and the finding of `blast' cells in the CSF. Immunoglobulin A was consistently absent from her serum and secretions. Necropsy showed extensive infiltration by a reticulum-cell sarcoma of the subarachnoid space, with tumour nodules on several cranial nerves and tumour infiltration of the tuber cinereum. The significance of the association between immunoglobulin A deficiency and neoplasia is discussed.

    Statistics from Altmetric.com

    Footnotes

    • 1 Present address: Department of the Regius Professor of Medicine, Radcliffe Infirmary, Oxford.

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.