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Carcinomatous neuromyopathy: 2. Immunological studies
  1. D. W. Paty1,
  2. M. J. Campbell2,
  3. D. Hughes
  1. M.R.C. Unit on Demyelinating Diseases, Newcastle General Hospital, Newcastle upon Tyne
  2. The Muscular Dystrophy Group Research Laboratories, Newcastle General Hospital, Newcastle upon Tyne

    An electrophysiological and immunological study of patients with carcinoma of the lung

    Abstract

    Significant cellular sensitivity to peripheral nerve antigens was found by MIF assay in 36% of patients with lung cancer (P<0·005) as compared with 62% of patients with peripheral neuropathy without neoplasia. No sensitivity was found in controls or the cancer sub-group without neuromuscular abnormality. The significance of these findings for an immune mechanism is discussed.

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    An electrophysiological and immunological study of patients with carcinoma of the lung

    Footnotes

    • 1 Present address: University Hospital, London, Ontario, Canada.

    • 2 Present address: Frenchay Hospital, Bristol, BS16 1LE.

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