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Extrapyramidal dysfunction with cerebral arteriovenous malformations
  1. Joao Lobo-Antunes,
  2. Melvin D. Yahr2,
  3. Sadek K. Hilal
  1. Clinical Center for Research in Parkinsonism and Allied Diseases, The Mount Sinai School of Medicine, Columbia University College of Physicians and Surgeons, N.Y., U.S.A.
  2. The Department of Neurosurgery, New York Neurological Institute, New York, N.Y., U.S.A.
  3. The Department of Neuroradiology, New York Neurological Institute, New York, N.Y., U.S.A.

    Abstract

    Arteriovenous malformations have only rarely been implicated as a cause of basal ganglia dysfunction. In four instances where such a lesion was uncovered, abnormal involuntary movements were present. In two, tremor involving the contralateral limbs occurred, while in others the head and neck were involved in dystonic movements and posture. The clinical and angiographic characteristics of these four patients have been assessed and are presented in detail in this report. The possible mechanism by which arteriovenous malformations may disturb the internal circuitry of the basal ganglia and induce symptoms are discussed.

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    Footnotes

    • 2 Address for reprints: Dr. Yahr, Mount Sinai School of Medicine.

    • 1 Supported in part by the Parkinson Disease Foundation, New York and NINDS Grant No. 05184.

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