Article Text


Benefit from adrenocorticotrophin in myasthenia gravis
  1. L. A. Liversedge,
  2. G. M. Yuill,
  3. I. M. S. Wilkinson,
  4. J. A. Hughes
  1. Department of Neurology, Royal Infirmary, Manchester


    Twenty-one of 29 patients suffering from myasthenia gravis derived benefit from a short intensive course of adrenocorticotrophin (ACTH). The mean duration of benefit was approximately six months. The best results were obtained in patients with a short history of myasthenia. Transient deterioration during the course of injections was encountered in some cases but necessitated assisted respiration only in patients with severe generalized weakness before treatment.

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