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Specificity of muscle antibodies in sera from patients with myasthenia gravis and from immunized rabbits
  1. Johan A. Aarli1,
  2. Olav Tønder,
  3. Otto Closs
  1. Department of Neurology, The Gade Institute, University of Bergen, Norway
  2. Broegelmann Research Laboratory for Microbiology, Department of Microbiology, The Gade Institute, University of Bergen, Norway

    Abstract

    Citric acid extracts (CAE) of human skeletal muscle were prepared. Myasthenia gravis sera giving high titres in indirect haemagglutination test with this antigen, were selected. Rabbit antisera to CAE were prepared. The specificity of the two types of muscle antibodies was compared. Both patient sera and the rabbit antisera gave positive reactions in serological tests for muscle antibodies, but a difference in serological specificity was found.

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    Footnotes

    • 1 Address for correspondence: Johan A. Aarli, Department of Neurology, 5016 Haukeland sykehus, Norway.

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