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Abnormal intrafusal muscle fibres in myotonic dystrophy: a study using serial sections
  1. M. Swash,
  2. K. P. Fox
  1. Section of Neurological Sciences, The London Hospital, London

    Abstract

    Studies of the extent and complexity of intrafusal muscle fibre splitting in myotonic dystrophy have been carried out in three spindles obtained at muscle biopsy, and in nine spindles found in the lumbrical muscle of a case that came to necropsy. It is suggested that splitting, due to mechanical stresses, leads to a regenerative response in the separated fragments.

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