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Value of exchangeable electrolyte measurement in the treatment of myasthenia gravis.
  1. M Critchley,
  2. K J Herman,
  3. M Harrison,
  4. R A Shields,
  5. L A Liversedge

    Abstract

    We have investigated electrolyte exchange in myasthenia gravis before and after corticotrophin therapy, using a four-isotope dilution technique. Clinical deterioration in patients on corticotrophin is associated with a fall of more than 20% in the intracellular potassium concentration, suggesting that all myasthenics so treated should be given potassium supplementation.

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