A quantitative assessment of post-ischaemic paraesthesiae has been made in 50 pellagrins and 20 healthy identical controls. The results show a higly significant diminution of the paraesthetic response in pellagrins. In pellagrins having peripheral neuropathy the depression of paraesthesiae was more marked than in those without peripheral neuropathy. There was no consistent relationship between severity of peripheral neuropathy and degree of depression of paraesthetic response.
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