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Late effects of subarachnoid haemorrhage on the response of the primate cerebral circulation to drug-induced changes in arterial blood pressure
  1. J. D. Pickard,
  2. D. P. J. Boisvert,
  3. D. I. Graham,
  4. W. Fitch
  1. Wellcome Surgical Research Institute, University of Glasgow, Glasgow
  2. The University Department of Neurosurgery, University of Glasgow, Glasgow
  3. The University Department of Neuropathology, University of Glasgow, Glasgow
  4. The University Department of Anaesthesia, University of Glasgow, Glasgow

    Abstract

    The ability of the cerebral circulation to maintain a constant level of cerebral blood flow with halothane-induced hypotension and angiotensin-induced hypertension was found to be impaired one week after subarachnoid haemorrhage in the baboon. No evidence of hypoxic brain damage was found. The clinical significance of these findings is discussed.

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