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Familial occurrence of moya-moya disease: report of three Japanese families
  1. Toshiki Kitahara,
  2. Naobumi Ariga,
  3. Akira Yamaura,
  4. Hiroyasu Makino,
  5. Yutaka Maki
  1. Department of Neurological Surgery, Chiba University School of Medicine, Chiba, Japan
  2. Department of Neurological Surgery, The University of Tsukuba School of Medicine, Ibaragi, Japan


    Three Japanese families with moya-moya disease in six patients are presented. These six patients were among 49 cases of confirmed moya-moya disease in our experience, and the familial incidence was more than 12%. A relatively high familial incidence (7%) was found in the total Japanese series emphasising the important hereditary components in the pathogenesis of the disease.

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