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Forearm exercise increases plasma hypoxanthine.
  1. V H Patterson,
  2. K K Kaiser,
  3. M H Brooke

    Abstract

    Plasma hypoxanthine was measured in three normal subjects during aerobic forearm exercise. The comparative increase of hypoxanthine greatly exceeded that of ammonia or lactate. It is proposed that hypoxanthine production reflects ATP breakdown in muscle. The test may prove useful in the investigation of patients with metabolic muscle disease.

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