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Cerebrospinal fluid oestrone in pseudotumour cerebri
  1. James O Donaldson*,
  2. Eva Horak
  1. Department of Neurology, University of Connecticut School of Medicine, Farmington, Connecticut, USA
  2. *Department of Internal Medicine, University of Connecticut School of Medicine, Farmington, Connecticut, USA
  3. Department of Laboratory Medicine,† University of Connecticut School of Medicine, Farmington, Connecticut, USA

    Abstract

    The concentration of oestrone in the cerebrospinal fluid (CSF) from obese young women with pseudotumour cerebri was much greater than predicted and found in normal subjects. Each woman with pseudotumour cerebri, and a high level of CSF oestrone and a CSF protein less than 0·2 g/l, had clinical improvement when treated with an 800 calorie/day diet and dexamethasone 2 mg/day.

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